Selective Extraction of Palladium(II) with Theophylline Derivatives.

New Theophylline Derivatives with Potential Pharmacological Activity

Theophylline, a methylxanthine compound, is known as an efficient bronchodilatator drug, having also anti-inflammatory and immunomodulatory effects. In order to improve its pharmacological profile and to reduce also the serious side effects that appear at high concentrations, new theophylline derivatives have been synthesized. The new compounds are obtained in two steps by the reaction of 8-sub...

Synthesis and Characterization of Some New Theophylline Derivatives

This paper presents the synthesis of some new theophylline derivatives with potential bronchodilatatory properties. The compounds were synthesized starting from theophylline and 8-R-theophyllines (R=Br, NO2, pyrrolidinyl, piperidinyl, morpholinyl, imidazolyl) that were reacted with 4-(2,3-epoxy-propyloxy)-acetanilide. The new compounds, which have not been mentioned in the literature concerning...

Anti-inflammatory effects of theophylline and selective phosphodiesterase inhibitors.

Theophylline has been used in the treatment of airway diseases, for more than 50 years with benefit thought to be derived from its ability to elicit bronchodilatation. Recent evidence has, however, suggested that theophylline possesses anti-inflammatory activity. The molecular mechanism of action remains unclear, although inhibition of the phosphodiesterase (PDE) enzyme, an enzyme which catalyz...

Selective extraction spectrophotometric determination

Selective Extraction and Determination of Di(2-ethylhexyl) Phthalate in Aqueous Solution by HPLC Coupled with Molecularly Imprinted Solid-phase Extraction

Surface Molecularly Imprinted Polymer (SMIP) for selective adsorption of di(2-ethylhexyl) phthalate(DEHP) was prepared on the surface of silica gel which was modified by aminopropyltriethoxysilane and acryloyl chloride in a two-step method. The prepared SMIP was used to prepare Molecularly Imprinted Solid-Phase Extraction (MISPE) column for selective extraction of DEHP from aqueous solution...